Recently, Wu Tianzhun, a researcher at the Institute of Advanced Microelectronics, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, and his research team successfully developed a high performance iridium oxide / platinum nano-cone composite coating with nanostructures. This high-performance composite coating effectively solves the problems of high electrochemical impedance, low charge storage capacity and low charge injection capability with electrode array and integration, and significantly improves the electrical stimulation performance of the nerve electrode. Related Research Results Electrodeposited Iridium Oxide on Platinum Nanocones for Improving Neural Stimulation Microelectrodes has been published online in the Electrochimica Acta. At the same time, the staged achievements of this work were collected by IEEE NEMS 2017 and nominated for the Finalist of best conference poster award.

Nerve stimulation / recording electrodes are widely used in the life sciences such as neurophysiology and brain science research, such as observation of neurological behaviors or treatment of neurological disorders such as blindness, deafness and Parkinson's disease. In order to provide clinical higher electrical stimulation / recording efficiency, neurostimulation / recording electrodes are moving toward integration and miniaturization, resulting in performance issues such as increased electrode impedance and decreased capacitance, which seriously degrade the performance of the microelectrode Safe to stimulate efficiency. At present, the coatings obtained by surface modification of microelectrode can not meet the requirements of low resistance, high charge storage capacity, high charge injection ability and long-term stability without increasing the electrode geometry.

Based on the above considerations, in the artificial retinal project leader Mark S. Under the guidance of Humayun, Wu Tianjun and his team members Zeng Qi, Xia Kai, Sun Bin and others successfully developed a high-performance iridium oxide / platinum nano-cone composite coating with nanostructures. From the perspective of improving electrode stability and stimulating efficiency, by introducing a layer of platinum nano cone on the surface of the microelectrode as an intermediate adhesion layer between the iridium oxide coating and the platinum substrate, and then slowly depositing a layer of iridium oxide having high capacitance characteristics . Among them, the platinum nano-tapered structure has the special advantage that on the one hand, the three-dimensional nano-tapered structure can provide an extremely large surface area to contain iridium oxide so as to prevent the iridium oxide from being excessively dense during deposition; on the other hand, The shape structure effectively improves the binding force between the iridium oxide and the platinum substrate, improves the long-term stability of the electrode coating, and effectively promotes the long-term implantation of the later microelectrode array.

The results show that the obtained high-performance iridium oxide / platinum nano-cone composite coating has a low impedance of 2.45 kΩ · cm 2 and a cathodic charge storage capacity of 22.29 mC · cm -2, which is larger than that of the platinum substrate 6 times more. In addition, the composite coating maintains stable impedance and cathode charge storage after 1 hour of ultrasonic oscillation or more than 1.7 * 107 pulses of electrical impulses, demonstrating superior mechanical stability and electrical Chemical stability. The research results effectively solve the shortcomings of the prior art and have strong operability. It is of great guiding significance to the development of microelectrode surface modification materials and nerve electrode stimulation / recording represented by artificial retina, and is expected to be widely applied to nerve prostheses and Efficient stimulation / recording electrodes and other fields.

The above research has been funded by the National Natural Science Foundation of China, Guangdong Innovation and Entrepreneurship Team, Shenzhen Peacock Team and other projects.

(A) Platinum nano cone intermediate adhesion layer; (b) Iridium oxide / platinum nano cone composite plating; (c) Cyclic voltammogram of ultrasonic test of iridium oxide / platinum nano cone composite plating; (d) Cyclic Voltammetry Comparison of Nano-Cone Composite Coatings After Electrical Pulse Stimulation


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