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Dry granulators largely avoid the complications of wet granulation technology. Dry granulation does not need to be humidified and then dried, which simplifies the pharmaceutical process. It does not need to add any adhesive to ensure the quality of the finished product. The pressure of the pressure roller can be adjusted intelligently with the increase or decrease of the material, which ensures that the compacted pellets have the same specifications and reduce the raw materials. waste.
In the dry granulator, all parts that can come in contact with the material are sealed and completely avoid the problems of drug quality caused by impurities such as lubricating oil in the material. In addition, the bulk density after granulation is significantly increased, drastically reducing dust, reducing material waste and making it easier to store and transport. Coupled with low energy consumption and zero waste emissions, the pollution of the pharmaceutical industry to the environment has been greatly reduced, and the economic benefits of the company have been greatly improved while its social image has been greatly improved.
The granulation process is an indispensable part of the pharmaceutical industry and has a significant role to play. The quality of granulation equipment directly affects the quality of pharmaceuticals. In the future development, pharmaceutical companies will have higher and higher technical requirements for granulators, and cleanliness and functional flexibility will also become the common pursuit targets of the industry. Although the dry granulation technology has been significantly developed today, the entire line of pharmaceutical granulation equipment (including three granulation processes: wet granulation, boiling granulation, and dry granulation) is more popular in the market, and the whole granulation equipment makes the wet product. The advantages of the respective equipments of the legal granulating machine and the boiling drying granulator are fully reflected. At the same time, the wet granulating machine and the dry granulating machine are combined with the system to ensure a higher granulation yield.
The whole granulation equipment of the granulation has the advantages of wet granulation, boiling granulation and dry granulation and is of great significance to the pharmaceutical granulation process. However, from the current point of view, there are very few companies in China that can provide solid pharmaceutical preparations and granulation equipment and solutions to pharmaceutical companies. Among them, Canaan Technology can provide customers with solid preparation granulation equipment and solutions. It is currently one of the few suppliers in China that can provide three granulation process complete line equipment and solutions. In addition, the GFL solid agent production line unit manufactured by Zhiyang Machinery upholds the traditional granulation process, and combines wet granulation, boiling drying granulation and wet granulation according to the technological features, scientifically and effectively combined to form a complete solid preparation. Production linkage line.
In the field of pharmaceutical granulation equipment, China's related technologies are still relatively lacking. China's pharmaceutical equipment companies still need to continue to exert efforts to strengthen investment in research and development, introduce and absorb advanced technologies, and design and produce more equipment that meets market demand.
The consumption of materials is high, the production cost is high, the intermediate links are numerous, the process is more complicated, the adhesive affects the quality of the finished medicine, and the waste discharge pollutes the environment... It is reported that the traditional wet granulation technology plays a major role in the pharmaceutical field while existing Many of the above defects have inevitably produced a series of problems. In order to avoid these problems, dry granulators started to emerge. It is the latest granulation method developed after the one-step granulation of the second-generation granulation method. It is an environmentally friendly granulation process that directly New equipment pressed into pellets.